Guo, NN Cover

Guo, 2011

Smrt cover

Smrt, 2007




  • Zhang P, Rausch C, Hastert FD, Boneva B, Filatova A, Patil SJ, Nuber UA, Gao Y, Zhao X, Cardoso MC. Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner. (2017) Nucleic Acids Res.Apr 25. doi: 10.1093/nar/gkx281. [Epub ahead of print] PMID: 28449087
  • Patzlaff NP, Nemec KM, Malone S, Li Y, Zhao X. Fragile X related protein 1 (FXR1P) regulates proliferation of adult neural stem cells. (2017) Hum Mol Genet  Apr 1;26(7):1340-1352. doi: 10.1093/hmg/ddx034.  Fragile X related protein 1 (FXR1P) regulates proliferation of adult neural stem cells. PMID: 28204491
  • Sun L, Zhao JY, Gu X, Liang L, Wu S, Mo K, Feng J, Guo W, Zhang J, Bekker A, Zhao X, Nestler EJ, Tao YX. Nerve injury-induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons.(2017) Pain. 2017 Mar 4. doi: 10.1097/j.pain.0000000000000894. [Epub ahead of print] PMID:28267064
  • Jobe EM*, Gao Y* (*equal contribution), Eisinger BE, Mladucky JK, Giuliani CC, Kelnhofer LE, and Zhao X. Methyl-CpG binding protein MBD1 regulates neuronal lineage commitment through maintaining adult neural stem cell identity (2017). Journal of Neuroscience. Jan 18;37(3):523-536. doi: 10.1523/JNEUROSCI.  PMID:26989163. (see news release). see a featured Journal Club discussing the impact of this paper on JN website.
  • Gao Y*, Wang F*, Eisinger BE*, Kelnhofer LE, Jobe EM, Zhao X. “Integrative Single-Cell Transcriptomics Reveal Molecular Networks Defining Neuronal Maturation during Postnatal Neurogenesis.” (2017) Cerebral Cortex. Mar 1;27(3):2064-2077. doi: 10.1093/cercor/bhw040. PMID:26989163. [* contributed equally (see news release)]




  • Wang F, Tidei JJ, Polich ED, Gao Y,  Zhao H, Perrone-Bizzozero NI, Weixiang Guo , Zhao X. Positive feedback between RNA-binding protein HuD and transcription factor SATB1 promotes neurogenesis. Proc Natl Acad Sci U S A plus (2015)
  • Guo W, Polich ED, Juan Su, J, Gao Y, Christopher, DM, Allan AM, Wang M, Wang F, Wang G, Zhao X. Fragile X Proteins FMRP and FXR2P control synaptic GluA1 expression and neuronal maturation via distinct mechanisms. Cell Reports. 2015. NIHMS690530, Publ.ID: CELREP1788
  • Gao Y#, Su J# (#,equal contributions), Guo W, Polich ED, Magyar DP, Xing Y, Li H, Smrt RD, Chang Q, Zhao X. Inhibition of miR-15a Promotes BDNF Expression and Rescues Dendritic Maturation Deficits in MeCP2-Deficient Neurons. Stem Cells. 2015 May;33(5):1618-29. PubMed PMID: 25639236; PubMed Central PMCID: PMC4409556.
  • Guo W, Tsujimura K, Otsuka I M, Irie K, Igarashi K, Nakashima K, Zhao X. VPA alleviates neurological deficits and restores gene expression in a mouse model of Rett syndrome. PLoS One. 2014;9(6):e100215. PubMed PMID: 24968028; PubMed Central PMCID: PMC4072629.
  • Li H, Zhong X, Chau KF, Santistevan NJ, Guo W, Kong G, Li X, Kadakia M, Masliah J, Chi J, Jin P, Zhang J, Zhao X, Chang Q. Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway. Nature Communications. 2014 Nov 25;5:5601. PubMed PMID: 25420914; PubMed Central PMCID: PMC4288926.
  • Chow CL, Guo W, Trivedi P, Zhao X, Gubbels SP.Characterization of a unique cell population marked by transgene expression in the adult cochlea of nestin-CreER(T2) /tdTomato-reporter mice. Journal of Comparative Neurology. 2015 Jun 1;523(10):1474-87. doi: 10.1002/cne.23747
  • Li Y, Zhao X.Concise review: Fragile X proteins in stem cell maintenance and differentiation. Stem Cells. 2014 Jul;32(7):1724-33. doi: 10.1002/stem.1698. (Concise Review). PubMed PMID: 24648324; PubMed Central PMCID: PMC4255947.
  • Hsieh J and Zhao X “Adult Neurogenesis: Genetics and Epigenetics in Adult Neuorgenesis” Cold Spring Harbor Laboratory Press (2015, book chapter)
  • Guo W and Zhao X. “Differential intrinsic and extrinsic regulations of the two Neurogenic Niches in the adult brain”.  Stem Cell Biology and Regenerative Medicine (Springer, Series Editor, Kursad Turksen) (2015 )






Before 2003 (when the Zhao Lab started)

(see a complete list of published work by Dr. Zhao: